5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine CAS 1228666-30-5
| CAS No. | 1228666-30-5 |
| Molecular Formula | C8H15FN2 |
| Molecular Weight | 158.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1228666-30-5) is a high-purity analytical reference standard with the molecular formula C8H15FN2 and a molecular weight of 158.22 g/mol.
The molecular framework of 5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine (C8H15FN2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H15FN2 |
| Molecular Weight | 158.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 7-fluoro-2-methyl-2H-indazole (CAS 1337881-42-1)
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