4-(3-Iodophenyl)morpholin-3-one CAS 1228775-74-3
| CAS No. | 1228775-74-3 |
| Molecular Formula | C10H10INO2 |
| Molecular Weight | 303.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(3-Iodophenyl)morpholin-3-one (C10H10INO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-(3-Iodophenyl)morpholin-3-one (CAS 1228775-74-3), molecular formula C10H10INO2 and molecular weight 303.10 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3-Iodophenyl)morpholin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10INO2 |
| Molecular Weight | 303.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodophenyl Standards
- N-(4-iodophenyl)-3-oxobutanamide (CAS 38418-25-6)
- 5-(2-Iodophenyl)-1,3,4-thiadiazol-2-amine (CAS 299934-10-4)
- n-(2-Iodophenyl)tetrahydro-2h-pyran-4-amine (CAS 1154889-82-3)
- n-(2-Iodophenyl)pivalamide (CAS 170959-10-1)
- n-(3-Iodophenyl)tetrahydro-2h-pyran-4-amine (CAS 179943-23-8)
- N-(2-iodophenyl)pentanamide (CAS 625408-18-6)
- N-(4-iodophenyl)-2-methylbutanamide (CAS 335398-08-8)
- N-(4-iodophenyl)-3-methylbutanamide (CAS 348594-29-6)
Recommended Standards
- 1-Bromo-2-(methylsulfonyl)-4-(trifluoromethyl)benzene (CAS 1215205-98-3)
- 3-Cyclopropoxy-4-iodobenzamide (CAS 1243321-52-9)
- 1-Bromo-3-(methylsulfonyl)-5-(trifluoromethyl)benzene (CAS 1215205-96-1)
- 2-Cyclopropoxy-4-iodobenzamide (CAS 1243354-33-7)
- 1-(4-Aminophenyl)cyclopropan-1-ol (CAS 1780535-62-7)
- 2-((Tetrahydro-2h-thiopyran-3-yl)amino)propane-1,3-diol (CAS 1491642-55-7)
- (3-Ethoxy-4,5-difluorophenyl)methanol (CAS 1443327-93-2)
- methyl (7S)-15-methoxy-12-oxo-2,4,11-triazatetracyclo[11.4.0.02,6.07,11]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate (CAS 1585235-96-6)
- Apixaban Impurity 61 (CAS CATO-C4X-108861)
- Ethyl 2-(6-Chloroimidazo[1,2-a]pyridin-2-yl)acetate (CAS 59128-02-8)
- Ethyl 3-cyano-4-fluorobenzoylformate (CAS 951888-16-7)
- N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(pent-4-ynoyl)-L-lysine (CAS 1159531-18-6)
- 5-Hydroxyisoquinoline-1-carboxylic acid (CAS 90800-37-6)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com