Ethyl 2-amino-5,6-difluoro-2,3-dihydro-1H-indene-2-carboxylate hydrochloride CAS 1229615-05-7
| CAS No. | 1229615-05-7 |
| Molecular Formula | C12H13F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-amino-5,6-difluoro-2,3-dihydro-1H-indene-2-carboxylate hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 2-amino-5,6-difluoro-2,3-dihydro-1H-indene-2-carboxylate hydrochloride (CAS 1229615-05-7) is a high-purity analytical reference standard with the molecular formula C12H13F2NO2HCl and a molecular weight of 277.69 g/mol.
The molecular framework of Ethyl 2-amino-5,6-difluoro-2,3-dihydro-1H-indene-2-carboxylate hydrochloride (C12H13F2NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-amino-5,6-difluoro-2,3-dihydro-1H-indene-2-carboxylate hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13F2NO2 HCl |
| Molecular Weight | 277.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- 3-(4-Bromo-2-fluorophenyl)-1,1,1-trifluoropropan-2-one (CAS 1341616-28-1)
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- Epon 828, Technical Grade (CAS 25068-38-6)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)prop-2-en-1-ol (CAS 116700-73-3)
- 1-(5-(4-FLUORO-3-METHYLPHENYL)PYRIMIDIN-2-YL)ETHAN-1-AMINE (CAS 1429182-15-9)
- N-[(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-4-sulfidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide (CAS 1579300-72-3)
- 2-Thioxo-1,2-dihydropyrimidine-4-carboxamide (CAS 155957-51-0)
- 1-(3-Methylbenzyl)cyclopropanamine (CAS 92146-66-2)
- N-Isopropyl-2-(3-nitrophenoxy)quinoline-6-carboxamide (CAS 921211-22-5)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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