Tamoxifen Impurity 18 CAS 123091-15-6
| CAS No. | 123091-15-6 |
| Molecular Formula | C11H17NO3S |
| Molecular Weight | 243.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tamoxifen Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Tamoxifen Impurity 18 (CAS 123091-15-6, C11H17NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tamoxifen Impurity 18 (C11H17NO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H17NO3S |
| Molecular Weight | 243.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Tamoxifen Standards
- Tamoxifen Impurity 20 (CAS CATO-C4X-123320)
- Tamoxifen Impurity 22 (CAS CATO-C4X-123322)
- Tamoxifen Impurity 26 (CAS CATO-C4X-123326)
- Tamoxifen Citrate Impurity 9 (CAS 69967-80-2)
- Tamoxifen Impurity 30 (CAS CATO-C4X-123330)
- Tamoxifen EP Impurity G (CAS 68047-07-4)
- Tamoxifen Impurity 21 (CAS CATO-C4X-123321)
- Tamoxifen Impurity 25 (CAS CATO-C4X-123325)
Recommended Standards
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