4-Oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylic acid CAS 123157-86-8

Purity 97%+In StockPharmaceutical Standards
CAS No.123157-86-8
Molecular FormulaC11H6F3NO3
Molecular Weight257.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylic acid CAS 123157-86-8 chemical structure

Description

4-Oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylic acid (CAS 123157-86-8), molecular formula C11H6F3NO3 and molecular weight 257.17 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C11H6F3NO3, 4-Oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 257.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H6F3NO3
Molecular Weight257.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1

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