(R)-Methyl 2-chloro-6-(3-methylmorpholino)pyrimidine-4-carboxylate CAS 1233339-69-9
| CAS No. | 1233339-69-9 |
| Molecular Formula | C11H14ClN3O3 |
| Molecular Weight | 271.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-Methyl 2-chloro-6-(3-methylmorpholino)pyrimidine-4-carboxylate.
(R)-Methyl 2-chloro-6-(3-methylmorpholino)pyrimidine-4-carboxylate (CAS 1233339-69-9), molecular formula C11H14ClN3O3 and molecular weight 271.70 g/mol, is a CATO reference standard with documented purity and traceability.
(R)-Methyl 2-chloro-6-(3-methylmorpholino)pyrimidine-4-carboxylate (C11H14ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-Methyl 2-chloro-6-(3-methylmorpholino)pyrimidine-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14ClN3O3 |
| Molecular Weight | 271.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Tert-butyl (E)-(4-chloro-3-((hydroxyimino)methyl)pyridin-2-yl)carbamate (CAS 1228670-07-2)
- 3-(4-Chlorophenyl)-4-phenylisoxazol-5(4H)-one (CAS 123476-71-1)
- 3-((2-Chloroquinolin-3-yl)methyl)pyrimidin-4(3H)-one (CAS 1227302-47-7)
- 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-chlorophenyl)ethan-1-one (CAS 124041-74-3)
- 4-(3-(Dimethylamino)pyrrolidin-1-yl)pyridin-3-amine (CAS 1342621-71-9)
- 3-(2-Bromo-1-(m-tolyl)ethoxy)tetrahydrofuran (CAS 1341797-62-3)
- 1-(2-Hydrazinylpropyl)piperidine (CAS 5844-29-1)
- N-(2,2,2-Trichloro-1-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl)formamide (CAS 93554-38-2)
- Rel-(2R,5R)-2-methyl-5-phenylmorpholine (CAS 1349828-91-6)
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- Pyridostigmine Impurity 4 (CAS CATO-C4X-26304)
- Liraglutide (CAS 204656-20-2)
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