((2R,3S,4S,5R)-4-Amino-5-(6-amino-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methanol CAS 123334-76-9
| CAS No. | 123334-76-9 |
| Molecular Formula | C10H13FN6O2 |
| Molecular Weight | 268.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
((2R,3S,4S,5R)-4-Amino-5-(6-amino-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methanol (CAS 123334-76-9), molecular formula C10H13FN6O2 and molecular weight 268.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of ((2R,3S,4S,5R)-4-Amino-5-(6-amino-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methanol (C10H13FN6O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures ((2R,3S,4S,5R)-4-Amino-5-(6-amino-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13FN6O2 |
| Molecular Weight | 268.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- 5-Fluoro-2-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)oxazolo[5,4-b]pyridine (CAS 1201323-97-8)
- (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)-4-fluorotetrahydrofuran-3-ol (CAS 125362-06-3)
- ((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methanol (CAS 114753-53-6)
- (E)-Diethyl (3-oxo-3-phenylprop-1-en-1-yl)phosphonate (CAS 70508-77-9)
- 4-([1,1-Biphenyl]-2-yloxy)-3-fluorophenylamine (CAS 946785-62-2)
- 2-(4-Methylpiperidin-1-yl)ethan-1-amine dihydrochloride (CAS 300578-42-1)
- 2-((6,8-Dibromo-2-ethylquinazolin-4-yl)oxy)ethyl acetate (CAS 88624-87-7)
- N-(tert-Butyl)hydroxylamine Hydrochloride (CAS 57497-39-9)
- 2-(Difluoromethoxy)-5-(pyridin-3-yl)pyridine (CAS 1214388-67-6)
- (R)-1-Methoxymethyl-propylamine hydrochloride (CAS 678182-79-1)
- 6- Chloro- 2- (ethylamino) pyridine- 3- carbonyl Fluoride (CAS 1092523-22-2)
- 2-(3,4,5-Trimethoxyphenyl)quinoline-4-carbohydrazide (CAS 327072-76-4)
- Diethyl (4-(aminomethyl)phenyl)phosphonate (CAS 1435463-00-5)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com