Ethyl 8-bromo-4-chloro-6-cyanoquinoline-3-carboxylate CAS 1233518-57-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1233518-57-4
Molecular FormulaC13H8BrClN2O2
Molecular Weight339.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 8-bromo-4-chloro-6-cyanoquinoline-3-carboxylate CAS 1233518-57-4 chemical structure

Description

The molecular framework of Ethyl 8-bromo-4-chloro-6-cyanoquinoline-3-carboxylate (C13H8BrClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Ethyl 8-bromo-4-chloro-6-cyanoquinoline-3-carboxylate (CAS 1233518-57-4) is a high-purity analytical reference standard with the molecular formula C13H8BrClN2O2 and a molecular weight of 339.57 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 8-bromo-4-chloro-6-cyanoquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H8BrClN2O2
Molecular Weight339.57 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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