1-(2-Bromophenyl)guanidine CAS 123375-81-5
| CAS No. | 123375-81-5 |
| Molecular Formula | C7H8BrN3 |
| Molecular Weight | 214.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-Bromophenyl)guanidine (C7H8BrN3) is characterized by a nitrile group, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 1-(2-Bromophenyl)guanidine (CAS 123375-81-5), a certified reference material (molecular formula C7H8BrN3, MW 214.06 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8BrN3 |
| Molecular Weight | 214.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromophenyl Standards
- (1Z)-1-(3-Bromophenyl)ethanone oxime (CAS 1434602-84-2)
- (E)-[(3-Bromophenyl)methylidene](methyl)oxidoazanium (CAS 16089-74-0)
- 1-(3-Bromophenyl)guanidine (CAS 870780-73-7)
- 1-(4-Bromophenyl)ethan-1-one oxime (CAS 5798-71-0)
- 1-(4-Bromophenyl)guanidine (CAS 67453-81-0)
- 2-(2-Bromophenyl)acetamide (CAS 65999-53-3)
- 2-(3-Bromophenyl)acetamide (CAS 60312-83-6)
- 2-(4-Bromophenyl)acetamide (CAS 74860-13-2)
Recommended Standards
- (S)-6-bromo-2,3-dihydrobenzofuran-3-amine (CAS 1228568-69-1)
- 1-(2-Bromopyridin-3-yl)propan-1-one (CAS 123534-58-7)
- (S)-5-bromo-2,3-dihydrobenzofuran-3-amine (CAS 1228565-88-5)
- 3-(Allyloxy)-2-bromopyridine (CAS 123552-77-2)
- 2-Phenylcyclobutan-1-amine (CAS 17293-44-6)
- N-(2,4-Difluorophenyl)-1-methyl-3-(trifluoromethyl)-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1H-pyrazole-4-carboxamide (CAS 400086-42-2)
- (R)-N-(4-(2-Chloro-1-hydroxyethyl)phenyl)-N-methylmethanesulfonamide (CAS 1176597-49-1)
- 1-Benzyl-6-tosyl-1,6-diazaspiro[3.3]Heptan-3-ol (CAS 1349199-70-7)
- 1-[(5-sulfanyl-1,3,4-oxadiazol-2-yl)methyl]azepan-2-one (CAS 790270-76-7)
- 5-Phenoxypentyl bromide (CAS 22921-72-8)
- 1-(4-Bromo-2-fluorophenyl)-2-methyl-1-propanol (CAS 1332651-40-7)
- 2-Methyl-5-(trifluoromethoxy)benzoyl chloride (CAS 1261445-13-9)
- Methyl 6-ethyl-2-(4-((2-methylpiperidin-1-yl)sulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride (CAS 1217176-92-5)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com