tert-Butyl 4-(2-fluoro-6-nitrophenoxy)piperidine-1-carboxylate CAS 1233958-46-7
| CAS No. | 1233958-46-7 |
| Molecular Formula | C16H21FN2O5 |
| Molecular Weight | 340.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
tert-Butyl 4-(2-fluoro-6-nitrophenoxy)piperidine-1-carboxylate (CAS 1233958-46-7) is a high-purity analytical reference standard with the molecular formula C16H21FN2O5 and a molecular weight of 340.35 g/mol.
The molecular framework of tert-Butyl 4-(2-fluoro-6-nitrophenoxy)piperidine-1-carboxylate (C16H21FN2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H21FN2O5 |
| Molecular Weight | 340.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-(4-fluoro-2-nitrophenoxy)piperidine-1-carboxylate (CAS 1233955-13-9)
- Ethyl 5-(4-fluorophenyl)-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate (CAS 126839-63-2)
- 4-(3-Fluoro-4-nitrophenoxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1232234-74-0)
- tert-Butyl 4-(3-fluoro-2-nitrophenoxy)piperidine-1-carboxylate (CAS 1286274-62-1)
- 2-carbamoylcyclopropanecarboxylic acid (CAS 716362-29-7)
- n-(3-Acetylphenyl)morpholine-4-carboxamide (CAS 341021-30-5)
- 3-(tert-Butoxy)-4-cyclopropoxyaniline (CAS 1243465-44-2)
- N-Ethyl 2-Bromo-4-nitroaniline (CAS 108485-08-1)
- N-(furan-2-ylmethyl)-2-phenoxyethan-1-amine (CAS 82395-70-8)
- (E)-1-(3,5-Difluoropyridin-2-yl)-2-methoxyethanone oxime (CAS 1075757-31-1)
- 1-(4-Bromo-5-methylthiophen-2-yl)ethan-1-one (CAS 36901-17-4)
- 2-(2-(4-Bromophenyl)-5-methyloxazol-4-yl)ethanol (CAS 328918-84-9)
- Pyrene-<SUP>13</SUP>C<SUB>16</SUB> (CAS 1228182-40-8)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com