Doxofylline Impurity 8 CAS 123524-29-8
| CAS No. | 123524-29-8 |
| Molecular Formula | C10H12N4O4 |
| Molecular Weight | 252.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Doxofylline Impurity 8 (CAS 123524-29-8) is a certified pharmaceutical impurity reference standard with the molecular formula C10H12N4O4 and a molecular weight of 252.23 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Doxofylline Impurity 8 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Doxofylline Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O4 |
| Molecular Weight | 252.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline Impurity 23 (CAS 27231-68-1)
- Doxofylline impurity 47 (CAS 180262-60-6)
- Doxofylline impurity 46 (CAS CATO-C4X-151346)
- Doxofylline Impurity 30 (CAS 5270-31-5)
- Doxofylline Impurity 1 (CAS 1429636-74-7)
- Doxofylline Impurity 28 (CAS 62637-09-6)
- Doxofylline Impurity 31 (CAS CATO-C4X-151331)
- Doxofylline Impurity 5 (CAS CATO-C4X-15135)
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