5-Fluoro-2-(trifluoromethoxy)aniline CAS 123572-63-4
| CAS No. | 123572-63-4 |
| Molecular Formula | C7H5F4NO |
| Molecular Weight | 195.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Fluoro-2-(trifluoromethoxy)aniline (CAS 123572-63-4), a certified reference material (molecular formula C7H5F4NO, MW 195.11 g/mol) for analytical method development and quality control.
The molecular framework of 5-Fluoro-2-(trifluoromethoxy)aniline (C7H5F4NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Fluoro-2-(trifluoromethoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F4NO |
| Molecular Weight | 195.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3-Fluoro-4-(trifluoromethoxy)aniline (CAS 1017779-69-9)
- 4-Fluoro-3-(trifluoromethoxy)aniline (CAS 113421-98-0)
- 3-Fluoro-2-methoxy-5-(trifluoromethyl)pyridine (CAS 1138011-20-7)
- 2-Fluoro-3-(trifluoromethoxy)aniline (CAS 1159512-64-7)
- 2-Fluoro-5-(trifluoromethoxy)aniline (CAS 116369-23-4)
- 2-Fluoro-6-(2,2,2-trifluoroethoxy)pyridine (CAS 1207670-88-9)
- 3-Fluoro-2-methoxy-6-(trifluoromethyl)pyridine (CAS 1214323-09-7)
- 5-Fluoro-2-methoxy-3-(trifluoromethyl)pyridine (CAS 1214351-11-7)
Recommended Standards
- 2-Fluoro-4-(trifluoromethoxy)aniline (CAS 123572-58-7)
- 4-Fluoro-2-(trifluoromethoxy)aniline (CAS 123572-66-7)
- 3-Fluoro-6-(trifluoromethyl)pyridine-2-methanol (CAS 1227601-29-7)
- 2-Chloro-5-(3-chloropropyl)thiophene (CAS 1250362-60-7)
- 2,6-Dibromo-3-fluorobenzyl chloride (CAS 1804933-18-3)
- 4-(4-(Pyridin-2-yl)thiazol-2-yl)butan-1-amine (CAS 1017423-03-8)
- 5,5’,5’’-Methanetriyltris(2-hydroxy-3-methylbenzoic Acid) (CAS 129749-43-5)
- 5-(4-Iodophenyl)-10,15,20-triphenyl-21H,23H-porphine (CAS 133513-05-0)
- 1-(3-Fluoro-4-methylphenyl)-3-{1-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}urea (CAS 1396799-64-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(o-tolyl)thiazol-5-yl)boronate (CAS 2223053-35-6)
- 1-(3,4-Dimethylphenyl)-2-(methylthio)propan-1-one (CAS 1184791-83-0)
- Dibutylamine acetate concentrate (CAS 19070-91-8)
- 2-Methyl-5-methylamino-phenol (CAS 55302-99-3)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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