Naphthol AS-BI CAS 1237-75-8
| CAS No. | 1237-75-8 |
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Naphthol AS-BI is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Naphthol AS-BI (CAS 1237-75-8), molecular formula C18H14BrNO3 and molecular weight 372.21 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Naphthol AS-BI under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Naphthol Standards
- Naphthol AS-OL phosphate (CAS 84522-15-6)
- Naphthol AS-G (CAS 91-96-3)
- Naphthol AS Phosphate (CAS 13989-98-5)
- Naphthol AS-MX Phosphate (CAS 1596-56-1)
- Naphthol AS-TR phosphate (CAS 2616-72-0)
- Naphthol AS Nonanoate (CAS 10523-82-7)
- Naphthol AS-OL Acetate (CAS 7128-79-2)
- 2-Naphthol-6,8-Disulfonic Acid (CAS 118-32-1)
Recommended Standards
- Proquinazid (CAS 189278-12-4)
- 4-(Difluoromethoxy)-4'-(trifluoromethoxy)-3-(trifluoromethyl)-1,1'-biphenyl (CAS 1261448-29-6)
- Lumateperone Impurity 42 (CAS CATO-C4X-220142)
- 2-(Difluoromethoxy)-2'-(trifluoromethoxy)-3-(trifluoromethyl)biphenyl (CAS 1261558-89-7)
- 6-(Hydroxymethyl)-1-methylpiperidin-2-one (CAS 20845-30-1)
- 4-(Difluoromethyl)-5-iodo-3-methylpicolinaldehyde (CAS 1806019-75-9)
- (S)-1-(3-(Benzyl(isopropyl)amino)pyrrolidin-1-yl)-2-chloroethanone (CAS 1354000-98-8)
- 4'-Ethyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 84392-24-5)
- 2-Methyl-1-(pyridin-4-yl)propan-1-one (CAS 60148-10-9)
- 2-(2-Bromo-4-(chloromethyl)-5-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805962-44-0)
- 4-Fluoroquinoline hydrochloride (CAS 1245643-64-4)
- 674788-53-5 1-Ethyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one MFCD04050119 (CAS 674788-53-5)
- Trelagliptin Impurity 8 (CAS CATO-C4X-10468)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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