6,6-Difluoro-7,8,9,10-tetrahydrobenzo[8]annulen-5(6H)-one CAS 1238627-55-8
| CAS No. | 1238627-55-8 |
| Molecular Formula | C12H12F2O |
| Molecular Weight | 210.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6,6-Difluoro-7,8,9,10-tetrahydrobenzo[8]annulen-5(6H)-one (CAS 1238627-55-8) is a high-purity analytical reference standard with the molecular formula C12H12F2O and a molecular weight of 210.22 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 6,6-Difluoro-7,8,9,10-tetrahydrobenzo[8]annulen-5(6H)-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 210.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12F2O |
| Molecular Weight | 210.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
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