7-bromo-2-chloro-5-fluoro-1H-benzimidazole CAS 1239720-18-3
| CAS No. | 1239720-18-3 |
| Molecular Formula | C7H11BrClFN2 |
| Molecular Weight | 257.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-bromo-2-chloro-5-fluoro-1H-benzimidazole (C7H11BrClFN2) is characterized by a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
7-bromo-2-chloro-5-fluoro-1H-benzimidazole (CAS 1239720-18-3) is a high-purity analytical reference standard with the molecular formula C7H11BrClFN2 and a molecular weight of 257.53 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-bromo-2-chloro-5-fluoro-1H-benzimidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11BrClFN2 |
| Molecular Weight | 257.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
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- 1-Methyl-4-(1-methylcyclohexyl)benzene (CAS 14962-12-0)
- 5-(2-Chloropyridin-4-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 266692-21-1)
- 4-Bromo-3-(difluoromethoxy)pyridine (CAS 1804910-68-6)
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- 3-Fluoro-1,5-dioxaspiro[5.5]undec-3-en-2-one (CAS 134878-53-8)
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