5-(2-Hydroxyethyl)-6-methyl-2-(pyrazin-2-yl)pyrimidin-4-ol CAS 1239736-46-9
| CAS No. | 1239736-46-9 |
| Molecular Formula | C11H12N4O2 |
| Molecular Weight | 232.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(2-Hydroxyethyl)-6-methyl-2-(pyrazin-2-yl)pyrimidin-4-ol (C11H12N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(2-Hydroxyethyl)-6-methyl-2-(pyrazin-2-yl)pyrimidin-4-ol (CAS 1239736-46-9) is a high-purity analytical reference standard with the molecular formula C11H12N4O2 and a molecular weight of 232.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12N4O2 |
| Molecular Weight | 232.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Hydroxyethyl Standards
- 1-(2-hydroxyethyl)-5-phenyl-1H-pyrazole-4-carboxylic acid (CAS 1292636-75-9)
- 2-(4-(2-Hydroxyethyl)piperazin-1-yl)nicotinonitrile (CAS 1017782-85-2)
- 6-(4-(2-Hydroxyethyl)piperazin-1-yl)nicotinonitrile (CAS 1017782-95-4)
- 3-(((2-Hydroxyethyl)amino)methyl)-6-methylquinolin-2(1H)-one (CAS 483286-64-2)
- N-2-Hydroxyethyl-N-(methyl-d3)-p-toluenesulfonamide (CAS 854634-39-2)
- n-(2-Hydroxyethyl)-2-(trifluoromethyl)benzamide (CAS 948720-21-6)
- N-(2-hydroxyethyl)-3-(trifluoromethyl)benzamide (CAS 948718-97-6)
- 2-(4-(2-Hydroxyethyl)piperazin-1-yl)benzonitrile (CAS 120116-37-2)
Recommended Standards
- 1-(4-Methoxybenzyl)-4-nitroso-1H-pyrazol-5-amine (CAS 1236202-77-9)
- 5-(2-Methoxyphenyl)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1239759-74-0)
- 3-(4-Methoxyphenyl)-4-methyl-1H-pyrazole-5-carboxylic acid (CAS 1234342-93-8)
- 5-(Benzyloxy)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1239775-52-0)
- 2-(1H-Benzo[d]imidazol-4-yl)-N-hydroxyacetimidamide (CAS 90558-64-8)
- 2,4-Dimethylfuran-3-carbonyl chloride (CAS 15139-39-6)
- 5-Amino-3-methoxypyrazine-2-carbonitrile (CAS 1137478-55-7)
- 3-((Diethylamino)methyl)benzaldehyde (CAS 911431-50-0)
- 1-(Pyrimidin-2-yl)piperidin-3-amine hydrochloride (CAS 1185309-66-3)
- Viomycin (CAS 32988-50-4)
- 5-Nitrobenzo[c][1,2,5]oxadiazole (CAS 18772-11-7)
- 5,6-Dichloro-2,3-dihydro-1H-inden-1-one (CAS 68755-31-7)
- Ethyl 4-bromo-2,5-difluorobenzoate (CAS 1383685-39-9)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com