2-Hydroxy-N-(3-methyl-1H-pyrazol-5-yl)-4-oxo-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline-1-carboxamide CAS 1240220-46-5
| CAS No. | 1240220-46-5 |
| Molecular Formula | C18H18N4O3 |
| Molecular Weight | 338.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Hydroxy-N-(3-methyl-1H-pyrazol-5-yl)-4-oxo-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline-1-carboxamide (CAS 1240220-46-5), molecular formula C18H18N4O3 and molecular weight 338.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Hydroxy-N-(3-methyl-1H-pyrazol-5-yl)-4-oxo-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline-1-carboxamide (C18H18N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18N4O3 |
| Molecular Weight | 338.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Hydroxy Standards
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Recommended Standards
- 1-(5-Methoxy-4-(3-morpholinopropoxy)-2-nitrophenyl)ethanone (CAS 1219937-96-8)
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- 1-Benzyl-3-(Cbz-amino)-2,5-pyrrolidinedione (CAS 1219424-59-5)
- Ethyl 2-[4-(4-methoxyphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]acetate (CAS 127828-84-6)
- 4-Cyclobutylpyrazole (CAS 1909308-43-5)
- N-(4-(2-(3,5-Dimethylpiperidin-1-yl)-2-oxoethyl)thiazol-2-yl)furan-2-carboxamide (CAS 921865-46-5)
- 1-(2-Aminothiazol-5-yl)-2-bromoethan-1-one (CAS 1377581-56-0)
- 2-(2-Methylpropyl)cyclopropane-1-carboxylic acid (CAS 1250198-67-4)
- Methyl 1-((2,6-dichloro-5-methoxypyrimidin-4-yl)oxy)cyclopropane-1-carboxylate (CAS 1572048-45-3)
- (E)-2-((2-morpholinothiazol-5-yl)methylene)hydrazine-1-carbothioamide (CAS 477845-62-8)
- (2S,3S)-3-((tert-butoxycarbonyl)amino)-3-(4-fluorophenyl)-2-hydroxypropanoic acid (CAS 959583-77-8)
- 2-(4-Chloro-3-methoxyphenyl)ethan-1-amine (CAS 96495-22-6)
- 4-Chloro-1,8-naphthalic anhydride (CAS 4053-08-1)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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