1-[(2-fluorophenyl)methyl]-1h-imidazol-2-amine hydrochloride CAS 1240527-63-2
| CAS No. | 1240527-63-2 |
| Molecular Formula | C10H10FN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-[(2-fluorophenyl)methyl]-1h-imidazol-2-amine hydrochloride (CAS 1240527-63-2), a certified reference material (molecular formula C10H10FN3HCl, MW 227.67 g/mol) for analytical method development and quality control.
The molecular framework of 1-[(2-fluorophenyl)methyl]-1h-imidazol-2-amine hydrochloride (C10H10FN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10FN3 HCl |
| Molecular Weight | 227.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related fluorophenyl Standards
- 3-[(3-fluorophenyl)methyl]pyrrolidine (CAS 1000198-80-0)
- 3-(3-Fluorophenyl)-3-oxopropanoic acid (CAS 1000530-96-0)
- Ethyl 1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-68-1)
- 1000574-26-4 2-(4-Fluorophenyl)-6-methylthio-4H-thiopyran-4-one MFCD09877819 (CAS 1000574-26-4)
- Ethyl 1-(2-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000575-18-7)
- 100074-04-2 5-(4-Fluorophenyl)-1-pentene MFCD11553774 (CAS 100074-04-2)
- 3-(2-Fluorophenyl)-4-hydroxyfuran-2(5H)-one (CAS 100074-44-0)
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Recommended Standards
- Sodium 2-(5-((6-(5-(tert-butyl)benzo[d]oxazol-2-yl)naphthalen-2-yl)oxy)pentyl)malonate (CAS 654080-03-2)
- 2-(4-Fluoro-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1147894-98-1)
- 3-Chloro-2-(4-methylpiperidin-1-yl)aniline (CAS 842965-35-9)
- Phosphocholine Chloride Calcium Salt Tetrahydrate (CAS 72556-74-2)
- 1-methyl-1H-pyrrolo[2,3-b]pyridine-3-sulfonyl chloride (CAS 1638761-60-0)
- [(2E)-3-Phenylprop-2-en-1-yl](propan-2-yl)amine (CAS 107261-81-4)
- 6-Amino-4-chloro-5-(difluoromethyl)picolinaldehyde (CAS 1805343-40-1)
- 3-(3,4-Dichlorophenyl)-3-methylbutan-1-amine (CAS 1226110-94-6)
- Ethylcarbamic Acid 1-(Phenylmethyl)-4-piperidinyl Ester (CAS 71879-62-4)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
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