1-[(3,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole CAS 1240564-83-3
| CAS No. | 1240564-83-3 |
| Molecular Formula | C10H7F2N3O2 |
| Molecular Weight | 239.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(3,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole.
CATO supplies 1-[(3,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240564-83-3), a certified reference material (molecular formula C10H7F2N3O2, MW 239.18 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-[(3,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[(3,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N3O2 |
| Molecular Weight | 239.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorophenyl Standards
- 1-(3,5-Difluorophenyl)-5-methyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1094411-40-1)
- 1-(3,4-difluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1152513-29-5)
- 1-[(2,6-Difluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240567-86-5)
- 1-[(2,6-Difluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240568-19-7)
- 1-[(3,5-Difluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240568-37-9)
- 1-[(3,4-Difluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240568-45-9)
- 1-[(2,4-Difluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240570-25-5)
- 1-[(2,4-Difluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240572-25-1)
Recommended Standards
- Ethyl 7-nitro-1,3-dioxaindane-5-carboxylate (CAS 1156940-88-3)
- 4-Nitrophenyl oxetan-3-yl carbonate (CAS 1134113-37-3)
- 2-(2-Nitrophenyl)-2-ureidoacetic acid (CAS 112273-62-8)
- 8-nitro-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxylic acid (CAS 1094424-70-0)
- N-(2-(Benzylthio)-4-oxo-1,4-dihydropyrimidin-5-yl)benzamide (CAS 109315-25-5)
- 3-[1-(3-chlorophenyl)-2,5-dimethyl-1h-pyrrol-3-yl]-2-cyanoprop-2-enoic acid (CAS 749907-05-9)
- 1-Methyl-1H-pyrimidin-2-one (CAS 3739-81-9)
- 3,5-Difluoro-4-formylphenylboronic Acid (CAS 870718-11-9)
- Pyridoxine Impurity 5 (CAS CATO-C4X-31085)
- 1-Phenyl-2-(piperidin-1-yl)ethan-1-ol (CAS 2480-56-0)
- (1H-benzo[d]imidazol-1-yl)(3,4-dimethoxyphenyl)methanone (CAS 333347-80-1)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- 6-Hydroxy-5-methyl-2-(2-(methylamino)ethyl)pyrimidin-4(3h)-one (CAS 1339379-07-5)
- Acetyl Dipeptide-1 (CAS 196604-48-5)
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