(R)-2-(3,5-Difluorophenyl)pyrrolidine CAS 1241683-70-4
| CAS No. | 1241683-70-4 |
| Molecular Formula | C10H11F2N |
| Molecular Weight | 183.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-2-(3,5-Difluorophenyl)pyrrolidine (CAS 1241683-70-4) is a high-purity analytical reference standard with the molecular formula C10H11F2N and a molecular weight of 183.20 g/mol.
Structurally, (R)-2-(3,5-Difluorophenyl)pyrrolidine (C10H11F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 183.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-2-(3,5-Difluorophenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11F2N |
| Molecular Weight | 183.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-(2,6-Difluorophenyl)pyrrolidine (CAS 1016529-46-6)
- 3-(2,4-Difluorophenyl)pyrrolidine (CAS 1092108-80-9)
- (S)-1-(2,3-difluorophenyl)but-3-en-1-amine (CAS 1181817-73-1)
- (S)-1-(3,5-difluorophenyl)but-3-en-1-amine (CAS 1181817-76-4)
- 1-(2,6-Difluorophenyl)cyclopropanemethanamine (CAS 1216908-25-6)
- (2S)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE (CAS 1217630-38-0)
- (S)-2-(3,5-Difluorophenyl)pyrrolidine (CAS 1217664-59-9)
- (S)-2-(2,4-difluorophenyl)pyrrolidine (CAS 1217667-72-5)
Recommended Standards
- (S)-5,8-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1241680-77-2)
- (R)-5,8-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1241683-88-4)
- (S)-5,7-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1241679-51-5)
- (R)-5,7-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1241684-13-8)
- 6-Amino-5-(2,2-dimethoxyethyl)-2-methylpyrimidin-4(1H)-one (CAS 1269293-64-2)
- 2-(2-Ethoxy-5-methylphenyl)ethanol (CAS 1378528-05-2)
- 1-(2,5-Difluorophenyl)-2-(propylthio)ethan-1-one (CAS 1157364-27-6)
- 2,3-Dichloro-4-iodo-6-(trifluoromethyl)pyridine (CAS 1824318-20-8)
- 2-Sulfanyl-1-[2-(trifluoromethyl)phenyl]-4,5-dihydro-1h-imidazol-5-one (CAS 852389-02-7)
- (1R,4S)-rel-N-[4-[(Acetyloxy)methyl]-2-cyclopenten-1-yl]acetamide (CAS 61865-50-7)
- Nicorandil Impurity 29 (CAS 16051-48-2)
- Methyl (1r,3r)-3-fluoro-3-phenylcyclobutane-1-carboxylate (CAS 1812175-18-0)
- (3S,4R,5S,6S)-6-Methyltetrahydro-2H-pyran-2,3,4,5-tetraol (CAS 87-96-7)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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