5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester CAS 124236-37-9

Description

Compared with other compounds in its class, the molecular weight of 211.18 g/mol gives 5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester (CAS 124236-37-9), a certified reference material (molecular formula C8H12F3NO2, MW 211.18 g/mol) for analytical method development and quality control.

The molecular framework of 5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester (C8H12F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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