Ethyl 2-(1H-pyrrol-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylate CAS 1242893-25-9
| CAS No. | 1242893-25-9 |
| Molecular Formula | C11H9F3N2O2S |
| Molecular Weight | 290.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 2-(1H-pyrrol-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylate (C11H9F3N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Ethyl 2-(1H-pyrrol-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 1242893-25-9), molecular formula C11H9F3N2O2S and molecular weight 290.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9F3N2O2S |
| Molecular Weight | 290.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- N,N'-BIs(4-fluorobenzoyl)methylhydrazine (CAS 1210782-09-4)
- (2R,5R)-5-(2-Fluorophenyl)-2,5-dimethyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine (CAS 1262859-67-5)
- 1-(N-(2,2,2-Trifluoroethyl)sulfamoyl)piperidine-4-carboxylic acid (CAS 1183142-42-8)
- 2-Fluoro-n-[2-(trifluoromethyl)cyclohexyl]pyridine-4-carboxamide (CAS 1292097-95-0)
- (2-(((Anthracen-9-ylmethyl)(methyl)amino)methyl)phenyl)boronic acid (CAS 156742-45-9)
- Lumiracoxib (CAS 220991-20-8)
- (E)-3-(Naphthalen-2-yl)acrylic acid (CAS 49711-14-0)
- Peramivir Impurity 35 (CAS 151907-80-1)
- 8-tert-Butyl 2-ethyl 3-oxo-8-azabicyclo[3.2.1]octane-2,8-dicarboxylate (CAS 1822617-22-0)
- 4-(4-Nitrophenyl)-4H-1,2,4-triazole (CAS 16759-47-0)
- n-Benzyl-1-azabicyclo[2.2.2]octan-3-amine (CAS 6530-11-6)
- 4-Methyl-2-(4h-1,2,4-triazol-3-yl)pyrimidine-5-carboxylic acid (CAS 1247418-14-9)
- 1-Phenylbuta-2,3-dien-1-one (CAS 69626-39-7)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com