3-Cyclopropoxy-4-(methylamino)picolinamide CAS 1243319-80-3
| CAS No. | 1243319-80-3 |
| Molecular Formula | C10H13N3O2 |
| Molecular Weight | 207.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Cyclopropoxy-4-(methylamino)picolinamide (CAS 1243319-80-3) is a high-purity analytical reference standard with the molecular formula C10H13N3O2 and a molecular weight of 207.23 g/mol.
The molecular framework of 3-Cyclopropoxy-4-(methylamino)picolinamide (C10H13N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Cyclopropoxy-4-(methylamino)picolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13N3O2 |
| Molecular Weight | 207.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Cyclopropoxy Standards
- 5-Cyclopropoxy-2-ethylnicotinic acid (CAS 1243290-00-7)
- 5-Cyclopropoxy-4-(methylamino)picolinamide (CAS 1243311-62-7)
- 2-Cyclopropoxy-5-methoxybenzamide (CAS 1243311-68-3)
- 5-Cyclopropoxy-6-(methylamino)picolinamide (CAS 1243315-94-7)
- 2-Cyclopropoxy-4-ethyl-1-nitrobenzene (CAS 1243318-17-3)
- 2-Cyclopropoxy-5-(methylamino)benzoic acid (CAS 1243319-59-6)
- 4-Cyclopropoxy-2-methoxybenzamide (CAS 1243320-28-6)
- 4-Cyclopropoxy-3-(methylamino)benzoic acid (CAS 1243327-18-5)
Recommended Standards
- 2-Amino-3-cyclopropoxy-N-methylisonicotinamide (CAS 1243318-19-5)
- 2-(Aminomethyl)-5-cyclopropoxybenzoic acid (CAS 1243323-37-6)
- 3-Amino-5-cyclopropoxy-N-methylpicolinamide (CAS 1243317-80-7)
- 2-Cyclopropoxy-3-(methylamino)benzoic acid (CAS 1243328-57-5)
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