5-Cyclopropoxy-6-fluoropicolinaldehyde CAS 1243329-85-2
| CAS No. | 1243329-85-2 |
| Molecular Formula | C9H8FNO2 |
| Molecular Weight | 181.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Cyclopropoxy-6-fluoropicolinaldehyde (CAS 1243329-85-2), molecular formula C9H8FNO2 and molecular weight 181.16 g/mol, is a CATO reference standard with documented purity and traceability.
5-Cyclopropoxy-6-fluoropicolinaldehyde (C9H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Cyclopropoxy-6-fluoropicolinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8FNO2 |
| Molecular Weight | 181.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyclopropoxy Standards
- 3-Cyclopropoxy-2-fluoroisonicotinaldehyde (CAS 1243344-29-7)
- 5-Cyclopropoxy-4-fluoronicotinaldehyde (CAS 1243356-10-6)
- 5-Cyclopropoxy-3-fluoropicolinaldehyde (CAS 1243358-24-8)
- 4-Cyclopropoxy-6-fluoropicolinaldehyde (CAS 1243446-06-1)
- 3-Cyclopropoxy-5-fluoropicolinaldehyde (CAS 1243471-78-4)
- 5-Cyclopropoxy-4-fluoropicolinaldehyde (CAS 1243472-29-8)
- 3-Cyclopropoxy-2-ethyl-4-fluoropyridine (CAS 1243310-48-6)
- (2-Cyclopropoxy-5-fluorophenyl)methanamine (CAS 1243322-85-1)
Recommended Standards
- 6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol (CAS 1240525-82-9)
- 2-Fluoro-4,5-dimethoxybenzonitrile (CAS 119396-88-2)
- 2-Amino-8-hydrazinyl-1H-purin-6(7H)-one (CAS 117086-97-2)
- 2,2,2-Trifluoro-1-(piperidin-3-yl)ethanone (CAS 1093759-81-9)
- 7-Bromobenzo[c][1,2,5]thiadiazole-4-carboxylic acid (CAS 3529-60-0)
- 1-Phenyl-2-(4-pyrimidinyl)ethanone (CAS 36912-83-1)
- 1-(4-Fluorophenyl)-4-morpholinobutan-1-one (CAS 3800-15-5)
- 1-(2,4,5-Trimethylphenyl)cyclopentan-1-amine (CAS 1368936-52-0)
- 3-(Diethylamino)propanenitrile (CAS 5351-04-2)
- 2-Methylpiperidin-1-amine (CAS 21399-44-0)
- 4,6-dihydrofuro[3,4-b]furan-3-carboxylic acid (CAS 164797-59-5)
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- (3R,4S,5R)-5-((benzoyloxy)methyl)-3-hydroxytetrahydrofuran-2,4-diyl dibenzoate (CAS 115459-51-3)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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