3-Cyclopropoxy-5-(trifluoromethyl)benzoic Acid CAS 1243345-22-3
| CAS No. | 1243345-22-3 |
| Molecular Formula | C11H9F3O3 |
| Molecular Weight | 246.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 3-Cyclopropoxy-5-(trifluoromethyl)benzoic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-Cyclopropoxy-5-(trifluoromethyl)benzoic Acid (CAS 1243345-22-3), a certified reference material (molecular formula C11H9F3O3, MW 246.18 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9F3O3 |
| Molecular Weight | 246.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Cyclopropoxy Standards
- 4-Cyclopropoxy-3-(trifluoromethyl)benzoic acid (CAS 1228583-70-7)
- 3-Cyclopropoxy-4-(trifluoromethyl)benzoic acid (CAS 1243325-22-5)
- 2-Cyclopropoxy-6-(trifluoromethyl)benzoic acid (CAS 1243381-07-8)
- 3-Cyclopropoxy-2-(trifluoromethyl)benzoic acid (CAS 1243400-62-5)
- 2-Cyclopropoxy-4-(trifluoromethyl)benzoic acid (CAS 1243473-18-8)
- 3-Cyclopropoxy-5-(trifluoromethyl)picolinamide (CAS 1243327-05-0)
- 4-Cyclopropoxy-2-(trifluoromethyl)nicotinamide (CAS 1243362-19-7)
- 4-Cyclopropoxy-3-(trifluoromethyl)picolinamide (CAS 1243380-98-4)
Recommended Standards
- Methyl 3-[4-(trifluoromethoxy)phenyl]acrylate (CAS 1226460-04-3)
- 1-[2-(aminomethyl)-3-methylbutyl]-2,4-dichlorobenzene (CAS 1226104-42-2)
- (R)-6-(Trifluoromethyl)chromane-3-carboxylic acid (CAS 1260603-28-8)
- 3-[3-methoxy-4-(trifluoromethyl)phenyl]prop-2-enoic acid (CAS 1214791-66-8)
- (R)-2-((R)-2-Aminopropanamido)-4-methylpentanoic acid (CAS 67392-69-2)
- 1-(Furan-3-yl)prop-2-en-1-ol (CAS 852998-61-9)
- 1-amino-4,4-dimethyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid hydrochloride (CAS 1803567-18-1)
- 1,3-Dibromo-2-chloro-4-fluorobenzene (CAS 1805026-31-6)
- 2-((1-(4-Chlorophenyl)-4,5,6,7-tetrahydro-1H-indazol-3-yl)oxy)acetonitrile (CAS 61088-02-6)
- 1-Bromo-2-(cyclopentyloxy)benzene (CAS 494773-69-2)
- 3-(P-tolylthio)propan-1-amine (CAS 67215-17-2)
- tert-Butyl 3-iodo-5-(1-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 1254926-81-2)
- (2R,4R)-2-methyltetrahydropyran-4-ol (CAS 1821720-33-5)
- Semaglutide (CAS 910463-68-2（free base）)
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