6-Bromo-4-cyclopropoxynicotinic acid CAS 1243346-21-5
| CAS No. | 1243346-21-5 |
| Molecular Formula | C9H8BrNO3 |
| Molecular Weight | 258.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-4-cyclopropoxynicotinic acid.
6-Bromo-4-cyclopropoxynicotinic acid (CAS 1243346-21-5), molecular formula C9H8BrNO3 and molecular weight 258.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 6-Bromo-4-cyclopropoxynicotinic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 258.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-4-cyclopropoxynicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8BrNO3 |
| Molecular Weight | 258.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-Bromo-5-cyclopropoxyisonicotinic acid (CAS 1243345-18-7)
- 6-Bromo-4-cyclopropoxypicolinic acid (CAS 1243346-38-4)
- 4-Bromo-5-cyclopropoxypicolinic acid (CAS 1243318-94-6)
- 1-Bromo-4-cyclopropoxy-2-nitrobenzene (CAS 1243350-13-1)
- 5-Chloro-2-methylpyrimidine (CAS 54198-89-9)
- Butane-1,4-diamine dihydrobromide (CAS 18773-04-1)
- 1-[4-(tert-Butyl)phenyl]cyclobutanamine (CAS 1096853-41-6)
- tert-Butyl 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)piperidine-1-carboxylate (CAS 796113-35-4)
- (3-(Dimethylamino)prop-1-yn-1-yl)boronic acid (CAS 763120-64-5)
- Avibactam Impurity 70 (CAS CATO-C4X-134870)
- 2-(Dimethylamino)-5-(methylamino)phenol (CAS 1243280-94-5)
- D-Glucopyranose, 4,6-O-(1R)-ethylidene-2,3-bis-O-(phenylmethyl)- (CAS 471863-88-4)
- 3-(4-Isopropylphenyl)acrylaldehyde (CAS 86604-05-9)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com