5-Chloro-2-(methylamino)phenol CAS 1243357-05-2
| CAS No. | 1243357-05-2 |
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 157.60 g/mol gives 5-Chloro-2-(methylamino)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-Chloro-2-(methylamino)phenol (CAS 1243357-05-2), a certified reference material (molecular formula C7H8ClNO, MW 157.60 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-2-(methylamino)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 157.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-(methylamino)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-N2-methylpyridine-2,3-diamine (CAS 100114-37-2)
- 4-Chloro-3-ethoxypyridine (CAS 1003711-81-6)
- 5-Chloro-2,3-dimethylpyridine 1-oxide (CAS 1015057-46-1)
- 2-Chloro-5-(methoxymethyl)pyridine (CAS 1016534-59-0)
- 3-Chloro-5-methoxyaniline (CAS 10272-06-7)
- 3-Chloro-5-(methylamino)phenol (CAS 1082113-30-1)
- (6-Chloro-2-methylpyridin-3-yl)methanol (CAS 1093879-95-8)
- 2-Chloro-4-methoxy-5-methylpyridine (CAS 1122090-84-9)
Recommended Standards
- 2-(Aminomethyl)-6-chlorophenol (CAS 1243282-04-3)
- 2-Chloro-3-(methylamino)phenol (CAS 1243361-73-0)
- 6-(Aminomethyl)-5-chloropyridin-2-amine (CAS 1240527-47-2)
- 2-Chloro-6-(methylamino)phenol (CAS 1243379-90-9)
- 2,5-Dichloroimidazo[4,5-b]pyridine (CAS 438190-90-0)
- (2-Methyl-1,3-benzoxazol-7-yl)methanol (CAS 136663-42-8)
- Levamisole-d5 Hydrochloride (CAS 1246819-64-6)
- 1-Propyl-1H-pyrrole-2-carbonitrile (CAS 101001-64-3)
- 1-(3,4-Dihydro-2H-pyrrol-5-yl)-1-(4-ethylphenyl)-3-phenylurea (CAS 886902-34-7)
- 5-Cyano-2-fluorobenzamide (CAS 916213-61-1)
- 2-(N-Benzylacetamido)acetic Acid (CAS 7662-79-5)
- 1-(4-Methoxyphenyl)-4-phenyl-1H-pyrazol-5-amine (CAS 1071093-28-1)
- 2-(Bromomethyl)benzenesulfonamide (CAS 153974-13-1)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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