4-Bromo-3-cyclopropoxy-2-fluoropyridine CAS 1243358-95-3
| CAS No. | 1243358-95-3 |
| Molecular Formula | C8H7BrFNO |
| Molecular Weight | 232.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromo-3-cyclopropoxy-2-fluoropyridine (C8H7BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Bromo-3-cyclopropoxy-2-fluoropyridine (CAS 1243358-95-3), a certified reference material (molecular formula C8H7BrFNO, MW 232.05 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7BrFNO |
| Molecular Weight | 232.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-Bromo-4-cyclopropoxy-2-fluoropyridine (CAS 1243356-18-4)
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- 4-Bromo-2-fluoro-6-methylbenzamide, 97% (CAS 1242156-51-9)
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- 5-Chloro-3-(difluoromethyl)-4-iodopyridin-2-amine (CAS 1806888-53-8)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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