2-(Aminomethyl)-3-cyclopropoxybenzamide CAS 1243368-45-7
| CAS No. | 1243368-45-7 |
| Molecular Formula | C11H14N2O2 |
| Molecular Weight | 206.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Aminomethyl)-3-cyclopropoxybenzamide (CAS 1243368-45-7) is a high-purity analytical reference standard with the molecular formula C11H14N2O2 and a molecular weight of 206.24 g/mol.
The molecular framework of 2-(Aminomethyl)-3-cyclopropoxybenzamide (C11H14N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Aminomethyl)-3-cyclopropoxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O2 |
| Molecular Weight | 206.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 3-Cyclopropoxy-N,6-dimethylpicolinamide (CAS 1243364-50-2)
- 2-Amino-4-cyclopropoxy-N-methylbenzamide (CAS 1243377-23-2)
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- 1-(Propan-2-yl)pyrrolidin-3-one (CAS 58039-28-4)
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- 6-Amino-1-ethyl-5-iodopyrimidine-2,4(1H,3H)-dione (CAS 1549752-63-7)
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- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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