4-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine CAS 1243369-59-6
| CAS No. | 1243369-59-6 |
| Molecular Formula | C13H16F3NO |
| Molecular Weight | 259.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine (CAS 1243369-59-6), molecular formula C13H16F3NO and molecular weight 259.27 g/mol, is a CATO reference standard with documented purity and traceability.
4-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine (C13H16F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16F3NO |
| Molecular Weight | 259.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(tert-Butyl)-5-cyclopropoxy-2-(trifluoromethyl)pyridine (CAS 1243355-18-1)
- 2-(tert-Butyl)-3-cyclopropoxy-4-(trifluoromethyl)pyridine (CAS 1243370-80-0)
- 5-(tert-Butyl)-3-cyclopropoxy-2-(trifluoromethyl)pyridine (CAS 1243310-76-0)
- 2-(tert-Butyl)-4-cyclopropoxy-3-(trifluoromethyl)pyridine (CAS 1243393-89-6)
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