2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine CAS 1243375-09-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1243375-09-8
Molecular FormulaC13H16F3NO2
Molecular Weight275.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine CAS 1243375-09-8 chemical structure

Description

The occurrence of 2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine (CAS 1243375-09-8), a certified reference material (molecular formula C13H16F3NO2, MW 275.27 g/mol) for analytical method development and quality control.

The molecular framework of 2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine (C13H16F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(tert-Butoxy)-4-cyclopropoxy-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H16F3NO2
Molecular Weight275.27 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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