2-Chloro-5-cyclopropoxy-4-fluoropyridine CAS 1243375-83-8
| CAS No. | 1243375-83-8 |
| Molecular Formula | C8H7ClFNO |
| Molecular Weight | 187.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Chloro-5-cyclopropoxy-4-fluoropyridine (CAS 1243375-83-8), a certified reference material (molecular formula C8H7ClFNO, MW 187.60 g/mol) for analytical method development and quality control.
2-Chloro-5-cyclopropoxy-4-fluoropyridine (C8H7ClFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-Chloro-5-cyclopropoxy-4-fluoropyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFNO |
| Molecular Weight | 187.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-fluoro-N-methylbenzamide (CAS 1067637-36-8)
- 5-Chloro-2-fluoro-N-methylbenzamide (CAS 1223412-83-6)
- 3-Chloro-4-cyclopropoxy-2-fluoropyridine (CAS 1243322-50-0)
- 5-Chloro-3-cyclopropoxy-2-fluoropyridine (CAS 1243363-55-4)
- 4-Chloro-3-cyclopropoxy-5-fluoropyridine (CAS 1243399-10-1)
- 3-Chloro-5-cyclopropoxy-2-fluoropyridine (CAS 1243404-92-3)
- 5-Chloro-4-cyclopropoxy-2-fluoropyridine (CAS 1243423-05-3)
- 2-Chloro-3-cyclopropoxy-6-fluoropyridine (CAS 1243425-76-4)
Recommended Standards
- 1-(5-Amino-2-chloro-4-fluorophenyl)ethan-1-one (CAS 101949-89-7)
- 3-Chloro-4-cyclopropoxy-5-fluoropyridine (CAS 1243445-84-2)
- 2-Chloro-4-(trifluoromethyl)pyridine 2-chloro-4-(trifluoromethyl)-pyridine 2-chloro-4-trifluoro-methylpyridine 2-chloro-4-trifluoro methylpyridine 2-chloro-4-trifluoromethylpyridine 2-chloro-4-trifluoromethyl-pyridine 81565-18-6 (CAS 81565-18-6)
- 3-Chloro-5-cyclopropoxy-4-fluoropyridine (CAS 1243445-95-5)
- Methyl 1-Benzyl-2,5-dihydropyrrole-3-carboxylate (CAS 101046-34-8)
- 3-(Bromomethyl)-1-methyl-1H-indole (CAS 1161233-34-6)
- Methyl 3-iodopicolinate (CAS 73841-41-5)
- 6-Phenyl-3-((3-(trifluoromethyl)phenyl)amino)-5,6,7-trihydro1H-indazol-4-hydrazone (CAS 1159976-61-0)
- 5-Chloro-2-methylphenol (CAS 5306-98-9)
- (3E)-4-(3-Hydroxyphenyl)-3-buten-2-one (3E)-4-(m-Hydroxyphenyl)-3-buten-2-one 22214-29-5 (CAS 22214-29-5)
- N2,N2,N4,N4-Tetraethyl-6-fluoropyrimidine-2,4-diamine (CAS 1648-44-8)
- 2-(chloromethyl)-5-methoxy-pyridine (CAS 75342-33-5)
- Ethyl (2E)-3-(3-cyanophenyl)-2-propenoate (CAS 125873-00-9)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com