1-Cyclopropoxy-4-iodo-2-(trifluoromethyl)benzene CAS 1243377-18-5
| CAS No. | 1243377-18-5 |
| Molecular Formula | C10H8F3IO |
| Molecular Weight | 328.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-Cyclopropoxy-4-iodo-2-(trifluoromethyl)benzene (CAS 1243377-18-5), a certified reference material (molecular formula C10H8F3IO, MW 328.07 g/mol) for analytical method development and quality control.
The molecular framework of 1-Cyclopropoxy-4-iodo-2-(trifluoromethyl)benzene (C10H8F3IO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F3IO |
| Molecular Weight | 328.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
Related Cyclopropoxy Standards
- 4-Cyclopropoxy-2-iodo-1-(trifluoromethyl)benzene (CAS 1243375-45-2)
- 1-Cyclopropoxy-3-iodo-2-(trifluoromethyl)benzene (CAS 1243398-29-9)
- 1-Cyclopropoxy-2-iodo-3-(trifluoromethyl)benzene (CAS 1243398-66-4)
- 4-Cyclopropoxy-1-iodo-2-(trifluoromethyl)benzene (CAS 1243444-95-2)
- 2-Cyclopropoxy-1-iodo-3-(trifluoromethyl)benzene (CAS 1243468-92-9)
- 4-Cyclopropoxy-2-iodo-3-(trifluoromethyl)pyridine (CAS 1243357-41-6)
- 3-Cyclopropoxy-2-iodo-5-(trifluoromethyl)pyridine (CAS 1243397-70-7)
- 3-Cyclopropoxy-4-iodo-2-(trifluoromethyl)pyridine (CAS 1243448-82-9)
Recommended Standards
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- Ferulic Acid Impurity 16 (CAS 98942-06-4)
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- 5-Chloro-3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 55828-85-8)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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