N-(5-Cyclopropoxy-4-(trifluoromethyl)pyridin-3-yl)methanesulfonamide CAS 1243377-25-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1243377-25-4
Molecular FormulaC10H11F3N2O3S
Molecular Weight296.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-Cyclopropoxy-4-(trifluoromethyl)pyridin-3-yl)methanesulfonamide CAS 1243377-25-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

N-(5-Cyclopropoxy-4-(trifluoromethyl)pyridin-3-yl)methanesulfonamide (CAS 1243377-25-4), molecular formula C10H11F3N2O3S and molecular weight 296.27 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, N-(5-Cyclopropoxy-4-(trifluoromethyl)pyridin-3-yl)methanesulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), N-(5-Cyclopropoxy-4-(trifluoromethyl)pyridin-3-yl)methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H11F3N2O3S
Molecular Weight296.27 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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