5-Cyano-2-cyclopropoxy-N-methylbenzamide CAS 1243378-18-8
| CAS No. | 1243378-18-8 |
| Molecular Formula | C12H12N2O2 |
| Molecular Weight | 216.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Cyano-2-cyclopropoxy-N-methylbenzamide (C12H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 5-Cyano-2-cyclopropoxy-N-methylbenzamide (CAS 1243378-18-8), a certified reference material (molecular formula C12H12N2O2, MW 216.24 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Cyano-2-cyclopropoxy-N-methylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O2 |
| Molecular Weight | 216.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Cyano Standards
- Ethyl 3-cyano-6-cyclopropylpicolinate (CAS 1221791-78-1)
- 3-Cyano-4-cyclopropoxy-N-methylbenzamide (CAS 1243401-61-7)
- 4-Cyano-2-cyclopropoxy-N-methylbenzamide (CAS 1243410-15-2)
- 2-Cyano-5-cyclopropoxy-N-methylbenzamide (CAS 1243479-66-4)
- 2-Cyano-3-cyclopropoxy-N-methylbenzamide (CAS 1243480-62-7)
- 3-cyano-4-(pyrrolidin-1-yl)benzoic acid (CAS 1311318-16-7)
- (2Z)-2-Cyano-3-{[(pyridin-4-yl)methyl]amino}but-2-enamide (CAS 303153-02-8)
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Recommended Standards
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- 4-Amino-6-ethylquinoline-3-carboxylic acid (CAS 1242260-53-2)
- 1-Methyl-5-(4-methylphenyl)-1h-pyrazole-3-carboxylic acid (CAS 124344-99-6)
- cis-3-Morpholinocyclobutanol hydrochloride (CAS 1807941-36-1)
- tert-Butyl 8-hydroxy-5-oxa-2-azaspiro[3.4]octane-2-carboxylate (CAS 1453315-99-5)
- 2-Fluoro-2-iodoacetic acid (CAS 471-45-4)
- Methyl 5-(hydroxymethyl)furan-2-carbimidate (CAS 89149-71-3)
- ((2-Methyltetrahydrofuran-3-yl)methyl)hydrazine (CAS 1512624-03-1)
- 76782-82-6 A838826 tert-butyl-dimethyl-prop-2-ynoxy-silane tert-butyl-dimethyl-prop-2-ynoxysilane (CAS 76782-82-6)
- Methyl 3-(4-piperidinylmethoxy)propanoatehydrochloride (CAS 1219979-58-4)
- 4-[(4-Chlorobenzenesulfinyl)methyl]-2-(pyridin-2-yl)-6-(pyrrolidin-1-yl)pyrimidine (CAS 306980-36-9)
- 3-((2-Amino-4-chlorophenyl)amino)propan-1-ol (CAS 62780-73-8)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
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