5-Cyclopropoxy-2-(methylthio)isonicotinaldehyde CAS 1243385-86-5
| CAS No. | 1243385-86-5 |
| Molecular Formula | C10H11NO2S |
| Molecular Weight | 209.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Cyclopropoxy-2-(methylthio)isonicotinaldehyde (CAS 1243385-86-5), molecular formula C10H11NO2S and molecular weight 209.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Cyclopropoxy-2-(methylthio)isonicotinaldehyde (C10H11NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Cyclopropoxy-2-(methylthio)isonicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11NO2S |
| Molecular Weight | 209.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Cyclopropoxy Standards
- 5-Cyclopropoxy-3-(methylthio)picolinaldehyde (CAS 1243350-03-9)
- 3-Cyclopropoxy-4-(methylthio)picolinaldehyde (CAS 1243361-99-0)
- 5-Cyclopropoxy-2-(methylthio)nicotinaldehyde (CAS 1243382-66-2)
- 5-Cyclopropoxy-4-(methylthio)nicotinaldehyde (CAS 1243459-08-6)
- 5-Cyclopropoxy-4-(methylthio)picolinaldehyde (CAS 1243466-96-7)
- 3-Cyclopropoxy-5-(methylthio)isonicotinaldehyde (CAS 1243468-61-2)
- 4-Cyclopropoxy-3-fluoro-N-methylbenzamide (CAS 1243348-16-4)
- 3-Cyclopropoxy-5-fluoro-N-methylbenzamide (CAS 1243409-49-5)
Recommended Standards
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- 4-(tert-Butyl)-3-cyclopropoxy-5-fluoropyridine (CAS 1243452-28-9)
- 2-(tert-Butyl)-3-cyclopropoxy-6-fluoropyridine (CAS 1243311-04-7)
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