5-Cyclopropoxy-4-iodo-N-methylnicotinamide CAS 1243391-59-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1243391-59-4
Molecular FormulaC10H11IN2O2
Molecular Weight318.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Cyclopropoxy-4-iodo-N-methylnicotinamide CAS 1243391-59-4 chemical structure

Description

The molecular framework of 5-Cyclopropoxy-4-iodo-N-methylnicotinamide (C10H11IN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

5-Cyclopropoxy-4-iodo-N-methylnicotinamide (CAS 1243391-59-4), molecular formula C10H11IN2O2 and molecular weight 318.11 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11IN2O2
Molecular Weight318.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentI-containing
Nitrogen Atoms2

Related Cyclopropoxy Standards

Recommended Standards

Why CATO?