3-Isopropoxy-2-(trifluoromethyl)phenol CAS 1243397-10-5
| CAS No. | 1243397-10-5 |
| Molecular Formula | C10H11F3O2 |
| Molecular Weight | 220.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Isopropoxy-2-(trifluoromethyl)phenol (CAS 1243397-10-5) is a high-purity analytical reference standard with the molecular formula C10H11F3O2 and a molecular weight of 220.19 g/mol.
The molecular framework of 3-Isopropoxy-2-(trifluoromethyl)phenol (C10H11F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11F3O2 |
| Molecular Weight | 220.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Isopropoxy Standards
- 1-Isopropoxy-4-(trifluoromethoxy)-benzene (CAS 1030471-18-1)
- 4-Isopropoxy-3-(trifluoromethyl)phenol (CAS 1243280-89-8)
- 2-Isopropoxy-4-(trifluoromethyl)phenol (CAS 1243353-40-3)
- Methyl 2-isopropoxy-3-vinylbenzoate (CAS 918870-66-3)
- Methyl 4-isopropoxy-3-vinylbenzoate (CAS 918870-83-4)
- 2-Isopropoxy-5-(piperidin-2-yl)pyridine (CAS 1352489-96-3)
- 2-Isopropoxy-5-(1-methylpyrrolidin-2-yl)pyridine (CAS 1352493-17-4)
- 5-Isopropoxy-1H-indazol-6-yl-6-boronic acid (CAS 2304634-23-7)
Recommended Standards
- 4-(PRopan-2-yloxy)-2-(trifluoromethyl)phenol (CAS 1243404-94-5)
- 3-(PRopan-2-yloxy)-5-(trifluoromethyl)phenol (CAS 1243454-18-3)
- 2-(PRopan-2-yloxy)-5-(trifluoromethyl)phenol (CAS 1243280-85-4)
- 2,2,2-Trifluoro-1-(3-methyl-1-propyl-1h-pyrazol-5-yl)ethan-1-one (CAS 1245773-03-8)
- 2-Methylbenzo[d]thiazole-6,7-diamine (CAS 101258-10-0)
- 3-Chloro-6-(trifluoromethyl)picolinonitrile (CAS 1214333-69-3)
- 2-(2-Phenylpyrimidin-5-yl)propanoic acid (CAS 122377-62-2)
- 1-methyl-1H-1,2,3-triazole-5-sulfonamide (CAS 1602410-39-8)
- 2,7-Dibromo-9,9-diheptyl-9H-fluorene (CAS 794548-76-8)
- 5-(Methylsulfonyl)benzo[d]oxazol-2(3H)-one (CAS 13920-98-4)
- 1-Bromo-2,4-difluoro-5-methoxybenzene (CAS 943831-06-9)
- (1R)-2-chloro-1-(naphthalen-1-yl)ethan-1-ol (CAS 1427565-86-3)
- 2-(Difluoromethyl)-3,5-dimethoxypyridine-6-methanol (CAS 1805050-83-2)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com