2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene CAS 1243397-58-1
| CAS No. | 1243397-58-1 |
| Molecular Formula | C10H8ClF3O |
| Molecular Weight | 236.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene.
2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene (CAS 1243397-58-1) is a high-purity analytical reference standard with the molecular formula C10H8ClF3O and a molecular weight of 236.62 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1-cyclopropoxy-3-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClF3O |
| Molecular Weight | 236.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-N-cyclopropyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1031619-96-1)
- 3-(3-Chloro-4-(trifluoromethyl)phenyl)propanal (CAS 1036396-40-3)
- 3-(2-Chloro-5-(trifluoromethyl)phenyl)propanal (CAS 1057670-86-6)
- 2-chloro-3-(4-(trifluoromethyl)phenyl)propanal (CAS 1149333-38-9)
- 4-Chloro-1-cyclopropoxy-2-(trifluoromethyl)benzene (CAS 1243313-35-0)
- 4-Chloro-2-cyclopropoxy-1-(trifluoromethyl)benzene (CAS 1243359-12-7)
- 1-Chloro-3-cyclopropoxy-5-(trifluoromethyl)benzene (CAS 1243360-23-7)
- 1-Chloro-3-cyclopropoxy-2-(trifluoromethyl)benzene (CAS 1243398-32-4)
Recommended Standards
- 1-Chloro-4-cyclopropoxy-2-(trifluoromethyl)benzene (CAS 1243452-58-5)
- 1-(4-Chloro-3,5-dimethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256482-56-0)
- 4-Chloro-6-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 1256784-33-4)
- 4-Chloro-7-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 1256955-47-1)
- Methyl 1-hydroxy-6-nitro-1H-indole-4-carboxylate (CAS 1082042-02-1)
- 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 142623-85-6)
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(((10-methylanthracen-9-yl)methyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 94617-17-1)
- 6-(1h-1,2,4-Triazol-1-yl)hexanoic acid (CAS 1341554-89-9)
- 4-Hydroxy-2-oxo-N,1-diphenyl-2,5-dihydro-1H-pyrrole-3-carboxamide (CAS 1221504-61-5)
- N-(2-methoxyphenyl)piperidin-4-amine (CAS 260360-16-5)
- N-benzyl-1-(5-methylfuran-2-yl)methanamine (CAS 130539-99-0)
- Isothiazolo[5,4-b]pyridin-3-ol (CAS 4337-60-4)
- 1-Methyl-2-(pyridin-3-yl)piperidine-3-carbaldehyde (CAS 1710703-19-7)
- Neuropeptide K, porcine (CAS 106441-70-7)
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