5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile CAS 1243397-63-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1243397-63-8
Molecular FormulaC10H7F3N2O
Molecular Weight228.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile CAS 1243397-63-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile.

CATO supplies 5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile (CAS 1243397-63-8), a certified reference material (molecular formula C10H7F3N2O, MW 228.17 g/mol) for analytical method development and quality control.

5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile (C10H7F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Cyclopropoxy-6-(trifluoromethyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7F3N2O
Molecular Weight228.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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