3-Cyclopropoxy-6-(trifluoromethyl)picolinic acid CAS 1243400-86-3
| CAS No. | 1243400-86-3 |
| Molecular Formula | C10H8F3NO3 |
| Molecular Weight | 247.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Cyclopropoxy-6-(trifluoromethyl)picolinic acid (CAS 1243400-86-3) is a high-purity analytical reference standard with the molecular formula C10H8F3NO3 and a molecular weight of 247.17 g/mol.
Structurally, 3-Cyclopropoxy-6-(trifluoromethyl)picolinic acid (C10H8F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 247.17 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F3NO3 |
| Molecular Weight | 247.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyclopropoxy Standards
- 3-Cyclopropoxy-4-(trifluoromethyl)picolinic acid (CAS 1243318-98-0)
- 1-Cyclopropoxy-3-nitro-2-(trifluoromethyl)benzene (CAS 1243325-35-0)
- 5-Cyclopropoxy-6-(trifluoromethyl)nicotinic acid (CAS 1243348-84-6)
- 4-Cyclopropoxy-5-(trifluoromethyl)picolinic acid (CAS 1243358-56-6)
- 4-Cyclopropoxy-6-(trifluoromethyl)nicotinic acid (CAS 1243359-02-5)
- 5-Cyclopropoxy-6-(trifluoromethyl)picolinic acid (CAS 1243364-35-3)
- 1-Cyclopropoxy-3-nitro-5-(trifluoromethyl)benzene (CAS 1243387-55-4)
- 5-Cyclopropoxy-3-(trifluoromethyl)picolinic acid (CAS 1243407-58-0)
Recommended Standards
- 4-Cyclopropoxy-2-nitro-1-(trifluoromethyl)benzene (CAS 1243407-75-1)
- 3-Cyclopropoxy-5-(trifluoromethyl)isonicotinic acid (CAS 1243408-89-0)
- 2-Cyclopropoxy-1-nitro-3-(trifluoromethyl)benzene (CAS 1243408-94-7)
- 4-Cyclopropoxy-1-nitro-2-(trifluoromethyl)benzene (CAS 1243448-73-8)
- (S)-Methyl 2-(5-(4-chlorophenyl)-7-methoxy-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)acetate (CAS 1300019-46-8)
- 2-((2,5-Dimethyl-1-(pyridin-2-yl)-1H-pyrrol-3-yl)methylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 444180-85-2)
- 1-Bromo-2,4-dichloro-3-nitrobenzene (CAS 1805578-60-2)
- 5-(1-Isopropylpiperidin-2-yl)pyridin-2(1H)-one (CAS 1352482-07-5)
- Amlodipine Impurity 144 (CAS CATO-C4X-1095144)
- 1-(Methylsulfonyl)-4-(trifluoromethyl)benzene (CAS 145963-48-0)
- 7-(propan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1049605-05-1)
- 5-(3-Cyanophenyl)nicotinic acid (CAS 893740-73-3)
- 3-fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1620575-05-4)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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