1-(tert-Butoxy)-3-cyclopropoxy-5-(trifluoromethyl)benzene CAS 1243440-48-3
| CAS No. | 1243440-48-3 |
| Molecular Formula | C14H17F3O2 |
| Molecular Weight | 274.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(tert-Butoxy)-3-cyclopropoxy-5-(trifluoromethyl)benzene.
1-(tert-Butoxy)-3-cyclopropoxy-5-(trifluoromethyl)benzene (CAS 1243440-48-3) is a high-purity analytical reference standard with the molecular formula C14H17F3O2 and a molecular weight of 274.28 g/mol.
Based on its molecular formula C14H17F3O2, 1-(tert-Butoxy)-3-cyclopropoxy-5-(trifluoromethyl)benzene contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H17F3O2 |
| Molecular Weight | 274.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related tert Standards
- 2-(tert-Butoxy)-4-cyclopropoxy-1-(trifluoromethyl)benzene (CAS 1243440-28-9)
- 1-(tert-Butoxy)-2-cyclopropoxy-4-(trifluoromethyl)benzene (CAS 1243440-55-2)
- 1-(4-Butoxy-2,6-dimethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443305-42-7)
- 2-{[(tert-butoxy)carbonyl]amino}-4-(diethylamino)butanoic acid (CAS 1404688-53-4)
- 2-Butoxy-4-ethyl-1-methyl-4-phenyl-1H-imidazol-5(4H)-one (CAS 88700-36-1)
- trans-1-Butoxy-4-(4-propylcyclohexyl)benzene (CAS 79709-84-5)
- 3-Butoxy-4-cyanobenzenesulfonyl chloride (CAS 942199-54-4)
- 1-Butoxy-3-chloro-2-ethoxy-5-nitrobenzene (CAS 1881296-42-9)
Recommended Standards
- 2-Methyl-1-{[4-(trifluoromethoxy)phenyl]methyl}piperazine (CAS 1240581-54-7)
- 1-(4-(Trifluoromethoxy)benzyl)piperidin-4-amine (CAS 1279219-09-8)
- 3-[4-(4-nitrophenyl)piperazin-1-yl]-3-oxopropanenitrile (CAS 122648-74-2)
- (S)-2-Amino-3-methyl-N-(3-(trifluoromethyl)benzyl)butanamide (CAS 1292747-03-5)
- N-(9-deoxy-epi-cinchonin-9-yl)picolinamide (CAS 1414851-55-0)
- 1-(Difluoromethyl)-2,4-dimethoxybenzene (CAS 1048382-72-4)
- 2-Amino-4-oxo-4H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 1000576-55-5)
- 3-(3-Chloro-4-nitrophenoxy)pyrrolidine (CAS 1249427-40-4)
- 4-(5-Bromopyridin-2-yl)tetrahydro-2H-pyran-4-carbonitrile (CAS 831203-30-6)
- 2-(Benzyloxy)-5-hydrazinylpyrazine (CAS 1260808-52-3)
- G-749 (CAS 1457983-28-6)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with butyl 2-propenoate, ethenylbenzene, 2-hydroxyethyl 2-propenoate and 2-propenoic acid (CAS 26061-99-4)
- 1-(3-(Aminomethyl)phenyl)-2-phenylethanone (CAS 1017781-67-7)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com