5-Bromo-3-cyclopropoxy-N-methylpicolinamide CAS 1243442-08-1
| CAS No. | 1243442-08-1 |
| Molecular Formula | C10H11BrN2O2 |
| Molecular Weight | 271.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 271.11 g/mol gives 5-Bromo-3-cyclopropoxy-N-methylpicolinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Bromo-3-cyclopropoxy-N-methylpicolinamide (CAS 1243442-08-1) is a high-purity analytical reference standard with the molecular formula C10H11BrN2O2 and a molecular weight of 271.11 g/mol.
The molecular framework of 5-Bromo-3-cyclopropoxy-N-methylpicolinamide (C10H11BrN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-3-cyclopropoxy-N-methylpicolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11BrN2O2 |
| Molecular Weight | 271.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 5-Bromo-4-cyclopropoxy-N-methylnicotinamide (CAS 1243441-86-2)
- 2-Bromo-5-cyclopropoxy-N-methylisonicotinamide (CAS 1243452-90-5)
- 6-Bromo-5-cyclopropoxy-N-methylpicolinamide (CAS 1243410-42-5)
- 5-Bromo-4-cyclopropoxy-N-methylpicolinamide (CAS 1243469-73-9)
- 2-Chloro-3-((2-ethoxyphenyl)amino)naphthalene-1,4-dione (CAS 64505-77-7)
- 2-(2-(Isopropylthio)ethyl)piperidine (CAS 1247225-52-0)
- Cyclopentyl (R)-2-amino-2-phenylacetate hydrochloride (CAS 914605-66-6)
- Lifitegrast Impurity 11 (CAS 1194550-67-8)
- Benzylidenetriphenyl-lambda5-phosphane (CAS 16721-45-2)
- 1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone (CAS 530740-47-7)
- Latamoxef Impurity 28 (CAS CATO-C4X-179828)
- 2-Methyl-4-phenylbutanenitrile (CAS 73475-33-9)
- 3-(Benzo[d][1,3]dioxol-5-yl)-5-(4-nitrophenyl)-1H-pyrazole (CAS 651717-31-6)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
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