6-Cyano-5-cyclopropoxy-N-methylpicolinamide CAS 1243445-63-7
| CAS No. | 1243445-63-7 |
| Molecular Formula | C11H11N3O2 |
| Molecular Weight | 217.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-Cyano-5-cyclopropoxy-N-methylpicolinamide (CAS 1243445-63-7) is a high-purity analytical reference standard with the molecular formula C11H11N3O2 and a molecular weight of 217.22 g/mol.
6-Cyano-5-cyclopropoxy-N-methylpicolinamide (C11H11N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H11N3O2 |
| Molecular Weight | 217.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Cyano Standards
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- 6-Cyano-3-cyclopropoxy-N-methylpicolinamide (CAS 1243392-23-5)
Recommended Standards
- 2-Cyano-5-cyclopropoxy-N-methylnicotinamide (CAS 1243409-10-0)
- 4-Cyano-5-cyclopropoxy-N-methylpicolinamide (CAS 1243449-20-8)
- 1-(3,5-Dimethylphenyl)-1H-1,2,4-triazole-3-carboxylic acid (CAS 1245644-75-0)
- 3,5-Dimethyl-1-(pyridin-3-yl)-1h-pyrazole-4-carboxylic acid (CAS 1245943-35-4)
- 1-[2-(2-Dimethylamino-5-iodo-pyrimidin-4-yl)-pyrrolidin-1-yl]-ethanone (CAS 1361115-97-0)
- S-(4-Chlorophenyl) methylcarbamothioate (CAS 29411-04-9)
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- 2-(1-(Benzo[d][1,3]dioxol-5-yl)-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid (CAS 1416348-55-4)
- 2-(Allylthio)-6-(benzo[d][1,3]dioxol-5-yl)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-92-3)
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