2-Cyclopropoxy-1-methyl-4-(trifluoromethyl)benzene CAS 1243448-32-9
| CAS No. | 1243448-32-9 |
| Molecular Formula | C11H11F3O |
| Molecular Weight | 216.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Cyclopropoxy-1-methyl-4-(trifluoromethyl)benzene (CAS 1243448-32-9), molecular formula C11H11F3O and molecular weight 216.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Cyclopropoxy-1-methyl-4-(trifluoromethyl)benzene (C11H11F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Cyclopropoxy-1-methyl-4-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11F3O |
| Molecular Weight | 216.20 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Cyclopropoxy Standards
- 1-Cyclopropoxy-3-methyl-5-(trifluoromethyl)benzene (CAS 1243288-74-5)
- 1-Cyclopropoxy-3-methyl-2-(trifluoromethyl)benzene (CAS 1243326-14-8)
- 1-Cyclopropoxy-4-methyl-2-(trifluoromethyl)benzene (CAS 1243355-53-4)
- 1-Cyclopropoxy-2-methyl-3-(trifluoromethyl)benzene (CAS 1243365-86-7)
- 2-Cyclopropoxy-1-methyl-3-(trifluoromethyl)benzene (CAS 1243442-09-2)
- 2-Cyclopropoxy-4-methyl-1-(trifluoromethyl)benzene (CAS 1243448-22-7)
- 4-Cyclopropoxy-3-methyl-2-(trifluoromethyl)pyridine (CAS 1243287-86-6)
- 5-Cyclopropoxy-2-methyl-4-(trifluoromethyl)pyridine (CAS 1243326-19-3)
Recommended Standards
- 3-(Cyclopropylmethyl)-4-(trifluoromethyl)phenol (CAS 1243461-34-8)
- 4-(Cyclopropylmethyl)-3-(trifluoromethyl)phenol (CAS 1243472-95-8)
- 5-(Pyrrolidin-2-yl)-2-(trifluoromethyl)pyridine (CAS 1245916-00-0)
- 1-(3,4,5-Trifluorophenyl)pentan-1-one (CAS 1247419-81-3)
- 1-Chloro-4-(isopropylsulfonyl)butane (CAS 128147-28-4)
- 2-Ethyl-3,5-dimethylpyridine (CAS 1123-96-2)
- 2-Hydrazinyl-4-(5-methylfuran-2-yl)pyrimidine (CAS 1410821-14-5)
- 4'-Nitro-[1,1'-biphenyl]-2-carbaldehyde (CAS 924868-84-8)
- n1-(2-Methoxybenzyl)-n2,n2-dimethylethane-1,2-diamine (CAS 626216-36-2)
- 3-Bromo-4-methoxy-5-(trifluoromethyl)aniline (CAS 1373920-70-7)
- 4-Amino-2-methyl-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 287917-60-6)
- Ethyl 2-amino-6-(2-hydroxyphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 914202-54-3)
- 9,10-Dimethyltetradecahydroacridine (CAS 114310-62-2)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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