1-Cyclopropoxy-2-(trifluoromethyl)benzene CAS 1243459-22-4
| CAS No. | 1243459-22-4 |
| Molecular Formula | C10H9F3O |
| Molecular Weight | 202.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Cyclopropoxy-2-(trifluoromethyl)benzene (CAS 1243459-22-4), a certified reference material (molecular formula C10H9F3O, MW 202.17 g/mol) for analytical method development and quality control.
Structurally, 1-Cyclopropoxy-2-(trifluoromethyl)benzene (C10H9F3O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 202.17 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O |
| Molecular Weight | 202.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Cyclopropoxy Standards
- 1-Cyclopropoxy-4-(trifluoromethyl)benzene (CAS 1243397-72-9)
- 1-cyclopropoxy-3-(trifluoromethyl)benzene (CAS 1243444-67-8)
- 5-Cyclopropoxy-2-isopropylnicotinonitrile (CAS 1243322-91-9)
- 4-Cyclopropoxy-6-isopropylnicotinonitrile (CAS 1243326-25-1)
- 4-Cyclopropoxy-6-isopropylpicolinonitrile (CAS 1243345-86-9)
- 3-Cyclopropoxy-2-isopropylisonicotinonitrile (CAS 1243352-62-6)
- 4-Cyclopropoxy-5-isopropylpicolinonitrile (CAS 1243357-39-2)
- 5-Cyclopropoxy-2-(dimethylamino)benzonitrile (CAS 1243363-85-0)
Recommended Standards
- 1-Butanone, 1-(3,4,5-trifluorophenyl)- (CAS 1247208-98-5)
- 1-Propanone, 2-methyl-1-(3,4,5-trifluorophenyl)- (CAS 1249509-28-1)
- 1-[4-(trifluoromethyl)phenyl]cyclopropan-1-ol (CAS 1224883-68-4)
- 2-(Trifluoromethyl)-2,3-dihydro-1H-inden-2-ol (CAS 1250172-63-4)
- Ethyl 3-(2,4-dinitrophenyl)propanoate (CAS 897544-77-3)
- tert-Butyl 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[4,5-d]azepine-6-carboxylate (CAS 1440954-94-8)
- 2-(1,3-Dioxolan-2-yl)-1-(4-isopropoxyphenyl)ethan-1-one (CAS 1263366-09-1)
- 1-(3-Aminoazetidin-1-yl)propan-1-one (CAS 1339189-44-4)
- Methyl 7-nitro-1H-indole-2-carboxylate (CAS 167027-28-3)
- Ethyl 3-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate (CAS 946152-71-2)
- 2-(Aminomethyl)-5-cyclopropoxynicotinic acid (CAS 1243371-56-3)
- 2-Amino-3-(4-chloro-1H-indol-3-yl)propanoic acid (CAS 118244-93-2)
- 8-Bromo-6-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 625394-68-5)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
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