Benzyl 5-cyanospiro[indoline-3,4'-piperidine]-1'-carboxylate CAS 1243474-73-8
| CAS No. | 1243474-73-8 |
| Molecular Formula | C21H21N3O2 |
| Molecular Weight | 347.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzyl 5-cyanospiro[indoline-3,4'-piperidine]-1'-carboxylate.
CATO supplies Benzyl 5-cyanospiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1243474-73-8), a certified reference material (molecular formula C21H21N3O2, MW 347.41 g/mol) for analytical method development and quality control.
Benzyl 5-cyanospiro[indoline-3,4'-piperidine]-1'-carboxylate (C21H21N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O2 |
| Molecular Weight | 347.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Benzyl Standards
- Ethyl 1-cyanospiro[2.5]Octane-1-carboxylate (CAS 724773-39-1)
- 2-Cyanospiro[3.5]nonane-2-carboxylic acid (CAS 1495416-47-1)
- 2-Cyanospiro[3.4]octane-2-carboxylic acid (CAS 1469129-54-1)
- methyl 1-cyanospiro[2.4]heptane-1-carboxylate (CAS 724773-41-5)
- 1-Cyanospiro[2.4]heptane-1-carboxylic acid (CAS 1374509-59-7)
- 2-Cyanospiro[3.3]heptane-2-carboxylic acid (CAS 1487965-23-0)
- 6-Cyanospiro[3.3]heptane-2-carboxylic acid (CAS 28114-89-8)
- 5-Cyanospiro[2.3]hexane-5-carboxylic acid (CAS 1491982-69-4)
Recommended Standards
- 1'-(tert-Butoxycarbonyl)spiro[chroman-4,4'-piperidine]-2-carboxylic acid (CAS 1228631-15-9)
- (1-Methyl-3-phenyl-1H-pyrazol-5-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone (CAS 1251577-65-7)
- (2S,4S)-4-(2-Allylphenoxy)-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid (CAS 1217669-69-6)
- 2-(10-Oxo-3,4,5,10-tetrahydrobenzo[b][1,6]naphthyridin-2(1H)-yl)-N-(o-tolyl)acetamide (CAS 1251616-51-9)
- N,N-Dimethyl-N′-[2-[[4-methyl-6-(1-piperidinyl)-2-pyrimidinyl]amino]ethyl]sulfamide (CAS 1226432-07-0)
- 4-(Chloromethyl)-1-(2-fluorophenyl)-1H-pyrazole (CAS 35715-72-1)
- 4-[(2-Bromoacetyl)amino]-N-(2-furylmethyl)-benzamide (CAS 1138443-40-9)
- 2-Bromo-5-(hydrazineylmethyl)pyridine (CAS 1260817-15-9)
- 1-(Pyridazin-3-yl)piperidin-3-amine (CAS 1250902-79-4)
- n-(2-Bromobenzyl)-2-methoxyethan-1-amine (CAS 875339-42-7)
- 1-(4-Chlorophenyl)-2-({5-[(2-phenoxyethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)ethan-1-one (CAS 303988-42-3)
- (E)-N-(2,4-dichlorophenyl)-2-(2-((3-hydroxyisobenzofuran-1-yl)methylene)hydrazinyl)-2-oxoacetamide (CAS 477852-85-0)
- 2-(Chloromethyl)-2,3-dihydro-1λ,2-benzothiazole-1,1,3-trione (CAS 13947-21-2)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com