4-Chloro-3-hydroxy-n-methylbenzamide CAS 1243475-42-4
| CAS No. | 1243475-42-4 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Chloro-3-hydroxy-n-methylbenzamide (CAS 1243475-42-4), a certified reference material (molecular formula C8H8ClNO2, MW 185.61 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H8ClNO2, 4-Chloro-3-hydroxy-n-methylbenzamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 185.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Chloro-3-hydroxy-n-methylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Chloro-5-hydroxy-N-methylbenzamide (CAS 1243473-55-3)
- 1-Chloro-3,5-dimethyl-2-nitrobenzene (CAS 124421-11-0)
- Methyl 2-(2-chloropyridin-3-yl)acetate (CAS 123222-09-3)
- Methyl 2-(chloromethyl)pyridine-4-carboxylate (CAS 125104-36-1)
- Tert-butyl (9-amino-3-oxabicyclo[3.3.1]Nonan-7-yl)carbamate (CAS 1823391-48-5)
- [6-(4-Isoxazol-5-yl-phenyl)-4-trifluoromethyl-pyridin-2-yl]-dimethyl-amine (CAS 1311280-04-2)
- tert-Butyl ((3-(tert-butyl)pyrrolidin-3-yl)methyl)carbamate (CAS 2080412-59-3)
- Tert-butyl (2-methoxycyclopentyl)carbamate (CAS 1484910-72-6)
- Cyclopropanesulfonic acid (3-ethynylphenyl)-amide (CAS 1378461-82-5)
- 4-(5-(Pyridin-4-yl)-1H-1,2,3-triazol-1-yl)-1,2,5-oxadiazol-3-amine (CAS 890093-95-5)
- 3-(Dimethylamino)-2-methoxyphenol (CAS 1243457-95-5)
- Desonide Impurity 17 (CAS CATO-C4X-130117)
- 8S64APH24W 88-95-9 Phthaloyl chloride 1,2-Phthaloyl dichloride 1,2-Benzenedicarbonyl dichloride Phthaloyl chloride (8CI) Phthaloyl dichloride 1,2-Bis(chlorocarbonyl)benzene EINECS 201-869-0 NSC 44611 Phthalic acid dichloride Phthalic chloride Phthalic dichloride Phthalyl chloride Phthalyl dichloride CCRIS 8625 UNII-8S64APH24W EC 201-869-0 (CAS 88-95-9)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
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