3-(4-Chlorophenyl)isoquinolin-1(2H)-one CAS 124394-22-5
| CAS No. | 124394-22-5 |
| Molecular Formula | C15H10ClNO |
| Molecular Weight | 255.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Chlorophenyl)isoquinolin-1(2H)-one (CAS 124394-22-5) is a high-purity analytical reference standard with the molecular formula C15H10ClNO and a molecular weight of 255.70 g/mol.
The molecular framework of 3-(4-Chlorophenyl)isoquinolin-1(2H)-one (C15H10ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClNO |
| Molecular Weight | 255.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Methyl 2-chloro-6-(piperazin-1-yl)isonicotinate (CAS 1227954-92-8)
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- 2,3,6,7-Tetrachlorodibenzo[b,d]thiophene (CAS 133513-19-6)
- 6-Methoxy-3,4-dihydroquinazolin-2(1H)-one (CAS 105763-69-7)
- Methyl Benzoate-d8 (CAS 91929-46-3)
- 7-Ethoxyquinolin-4-amine (CAS 1021439-79-1)
- Diethyl 5-(3,4-dimethoxybenzamido)-3-methylthiophene-2,4-dicarboxylate (CAS 5657-82-9)
- 2-(1,3-thiazol-2-yl)propanenitrile (CAS 101010-75-7)
- 4-Methoxy-2-methylquinolin-8-ol (CAS 167834-50-6)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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