| CAS No. | 1245091-90-0 |
| Molecular Formula | C12H10BrClN2O2 |
| Molecular Weight | 329.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 329.58 g/mol gives Ethyl 1-(2-bromophenyl)-5-chloro-1H-pyrazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 1-(2-bromophenyl)-5-chloro-1H-pyrazole-4-carboxylate (CAS 1245091-90-0) is a high-purity analytical reference standard with the molecular formula C12H10BrClN2O2 and a molecular weight of 329.58 g/mol.
Ethyl 1-(2-bromophenyl)-5-chloro-1H-pyrazole-4-carboxylate (C12H10BrClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 1-(2-bromophenyl)-5-chloro-1H-pyrazole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H10BrClN2O2 |
| Molecular Weight | 329.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |